Single-product skincare is having a moment, and 37 Actives‘ Extreme Actives is the most credible ‘one bottle does it all’ I’ve tested.
The premise
Thirty-seven active ingredients in a single high-performance treatment cream. Peptides, antioxidants, growth factors, hyaluronic acid, and a long list of botanicals. The idea is that you don’t layer six products to address six concerns — one well-formulated cream does the work.
How it wears
Rich texture but not occlusive. Use morning and night after cleansing, on its own. Skin tolerates it without flaking, and the rich formula doesn’t pill under makeup.
The verdict
The price stings, but the math works out — you skip serums, eye creams, and treatments. If you want to simplify, this is the simplification.

